
帕金森氏病(PD)是一种渐进的神经退行性疾病。这不仅意味着它随着时间的流逝而变得越来越糟,而且其“进步”性质也使患者的治疗方式变得复杂。
那是因为帕金森氏症早期阶段的人需要与高级阶段的人明显不同。尽管医生有帮助识别疾病的严重程度和进展的工具,但这些工具并不能充分识别患者从一个阶段传递到另一个阶段的何时通过,这可能会导致受PD影响的人的最佳治疗方案。
“With Parkinson’s, people go from being essentially healthy people who have a little bit of tremor or stiffness, to over the course of the disease potentially experiencing symptoms such as cognitive impairment, psychosis and even becoming completely bedridden – and yet we try and treat that as one disease,” says Peter Schmidt, Ph.D., senior vice president & chief research and clinical officer, Parkinson’s Foundation. “This is why a better staging model is critical.”
为了更好地评估患者疾病进展的阶段,著名的疾病专家和Abbvie Heor和医学事务与帕金森基金会(PF)和治愈帕金森信托(CPT)创建一个分期模型,以全面评估帕金森氏症的生理和心理症状。该合作导致了一种新的护理点筛选工具,旨在将患者护理从“测量到管理”。
该工具将在第21届国际帕金森氏病和运动障碍国际大会(2017年6月3日至4日)介绍,定于八点驾驶帕金森的卓越基金会中心今年在美国和欧洲。
This tool has been designed for every clinician – from a general practitioner to the world’s foremost movement disorder specialist – to be able to use a questionnaire to place patients into three categories: 1) those for whom oral treatments are controlling PD symptoms properly, 2) those who may need optimizing of oral medications to control symptoms, and 3) those who are no longer responding to these therapies and may benefit from advanced PD treatments.
施密特说:“能够确定人们从一种治疗范式过渡到另一种治疗范式的观点非常重要。”“尤其是当我们想到一个未来时,希望我们能为帕金森岛掉下来的更多更好的治疗疗法。”